Detective Sherlock Holmes and Dr. John Watson join forces to investigate a murder at Buckingham Palace. They soon learn that they have only four days to solve the case, or the queen will become the next victim.
| Directing | Etan Cohen | Director |
| Production | Lucinda Syson | Casting |
| Writing | Arthur Conan Doyle | Characters |
| Camera | Oliver Wood | Director of Photography |
| Art | James Hambidge | Production Design |
| Editing | Dean Zimmerman | Editor |
| Editing | Erik Jessen | Editor |
| Costume & Make-Up | Beatrix Aruna Pasztor | Costume Design |
| Sound | Mark Mothersbaugh | Original Music Composer |
| Production | Jamie Christopher | Producer |
| Production | Jessica Elbaum | Executive Producer |
| Production | Will Ferrell | Producer |
| Production | Chris Henchy | Executive Producer |
| Production | Adam McKay | Producer |
| Production | Jimmy Miller | Producer |
| Production | David Mimran | Executive Producer |
| Production | Matt Riley | Executive Producer |
| Production | Jordan Schur | Executive Producer |
| Production | Clayton Townsend | Producer |
| Art | David Allday | Supervising Art Director |
| Art | Toby Britton | Art Direction |
| Art | Sue Whitaker | Art Direction |
| Art | Christopher Wyatt | Art Direction |
| Art | Niamh Coulter | Set Decoration |
| Costume & Make-Up | Autumn Butler | Makeup Artist |
| Costume & Make-Up | Bridget Cook | Hairstylist |
| Costume & Make-Up | Renata Gilbert | Makeup Artist |
| Costume & Make-Up | Belinda Hodgson | Key Makeup Artist |
| Costume & Make-Up | Nadia Homri | Makeup Artist |
| Costume & Make-Up | Tracy Smith | Key Hair Stylist |
| Costume & Make-Up | Jeremy Woodhead | Makeup Designer |
| Visual Effects | Hayley J Williams | Special Effects Supervisor |
| Art | Buddie Wilkinson | Standby Property Master |
| Visual Effects | Brooke Lyndon-Stanford | Visual Effects Supervisor |
| Art | Soren Bendt Aaboe Pedersen | Storyboard Artist |
| Crew | Joe Watts | Stunts |
| Crew | Jo McLaren | Stunt Coordinator |
| Camera | Fraser Taggart | Second Unit Director of Photography |
| Directing | Jamie Christopher | First Assistant Director |
| Crew | Tolga Kenan | Stunts |
| Crew | Tolga Kenan | Utility Stunts |
| Crew | Marc Mailley | Stunts |
| Writing | Etan Cohen | Writer |
| Directing | Matthew Sharp | Assistant Director |
