A listless Wade Wilson toils away in civilian life with his days as the morally flexible mercenary, Deadpool, behind him. But when his homeworld faces an existential threat, Wade must reluctantly suit-up again with an even more reluctant Wolverine.
| Writing | Fabian Nicieza | Characters |
| Writing | Rob Liefeld | Characters |
| Production | Kevin Feige | Producer |
| Directing | Shawn Levy | Director |
| Writing | Rhett Reese | Writer |
| Writing | Paul Wernick | Writer |
| Production | Louis D'Esposito | Executive Producer |
| Production | Ryan Reynolds | Producer |
| Writing | Ryan Reynolds | Writer |
| Production | Shawn Levy | Producer |
| Writing | Zeb Wells | Writer |
| Production | Sarah Halley Finn | Casting |
| Writing | Shawn Levy | Writer |
| Camera | George Richmond | Director of Photography |
| Art | Ray Chan | Production Design |
| Costume & Make-Up | Mayes C. Rubeo | Costume Design |
| Directing | George Cottle | Second Unit Director |
| Sound | Rob Simonsen | Original Music Composer |
| Production | Mitchell Bell | Co-Producer |
| Art | Naomi Moore | Set Decoration |
| Sound | Dave Jordan | Music Supervisor |
| Editing | Shane Reid | Editor |
| Production | Lauren Shuler Donner | Producer |
| Production | Wendy Jacobson | Executive Producer |
| Production | Mary McLaglen | Executive Producer |
| Production | Josh McLaglen | Executive Producer |
| Production | Rhett Reese | Executive Producer |
| Production | Paul Wernick | Executive Producer |
| Production | George Dewey | Executive Producer |
| Production | Simon Kinberg | Executive Producer |
| Production | Jonathon Komack Martin | Executive Producer |
| Visual Effects | Swen Gillberg | Visual Effects Supervisor |
| Editing | Dean Zimmerman | Editor |
| Crew | George Cottle | Stunt Coordinator |
| Art | Alex Bowens | Art Direction |
| Costume & Make-Up | Claire Pritchard | Hair Designer |
| Directing | Josh McLaglen | First Assistant Director |
| Costume & Make-Up | Bill Corso | Makeup Designer |
| Costume & Make-Up | Sean Flanigan | Hairstylist |
| Crew | Martin Bell | Visual Effects Art Director |
| Sound | Samson Neslund | Sound Designer |
| Costume & Make-Up | Graham Churchyard | Costume Design |
| Art | William Groebe | Storyboard Artist |
| Sound | Ryan Cole | Supervising Sound Editor |
| Crew | Colin Follenweider | Stunt Coordinator |
| Crew | Marvin Berrembou | Stunts |
| Crew | Tom Buckley | Stunt Driver |
| Crew | Adrian Derrick-Palmer | Stunts |
| Crew | Josh Dyer | Stunts |
| Sound | Eric A. Norris | Sound Designer |
| Art | Jeremy Simser | Storyboard Artist |
| Lighting | Wayne Shields | Gaffer |
| Crew | Mark Strange | Stunts |
| Crew | Daniel Stevens | Stunt Double |
| Crew | Ailís Smith | Stunts |
| Crew | Lauriane Rouault | Stunts |
| Crew | Shane Roberts | Stunts |
| Crew | Oleg Podobin | Stunts |
| Crew | Maureen Lavoyer | Stunts |
| Crew | Bogdan Kumšackij | Stunts |
| Crew | Ayesha Hussain | Stunts |
| Crew | Jessica Hooker | Stunts |
| Crew | Matthew Bell | Stunts |
| Sound | Doc Kane | ADR Mixer |
| Crew | Tony Christian | Stunts |
| Writing | Len Wein | Characters |
| Writing | John Romita Sr. | Characters |
| Writing | Herb Trimpe | Characters |
| Writing | Roy Thomas | Characters |
| Costume & Make-Up | Geoff Redknap | Key Hair Stylist |
| Costume & Make-Up | Geoff Redknap | Key Makeup Artist |
| Costume & Make-Up | Robb Crafer | Other |
| Crew | Alex Kyshkovych | Stunt Double |
| Crew | Christina Petrou | Stunts |
| Crew | Erol Ismail | Stunts |
| Crew | James Cox | Stunts |
| Crew | Jonny James | Stunts |
| Crew | Billy Clements | Stunts |
| Crew | Henry Delaney | In Memory Of |
| Sound | Lora Hirschberg | Sound Re-Recording Mixer |
| Visual Effects | Lisa Marra | Visual Effects Producer |
| Crew | Daniel Medina Ramos | Stunts |
| Crew | Jade Lye | Stunts |
| Crew | Nilly Cetin | Stunts |
| Crew | Eduardo Gago Muñoz | Stunts |
| Crew | Chloe Kibble | Stunts |
| Crew | Curtis Rowland Small | Stunts |
| Crew | Jessica Walker | Stunts |
